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Clinical implication of difficulty initiating sleep in patients with heart failure

Published:November 03, 2022DOI:https://doi.org/10.1016/j.jjcc.2022.10.004
      Heart failure and sleep disorders have a deep association with each other. Amisaki and colleagues demonstrated that an increase in left atrial pressure indicated by higher E/e′ ratio and hypertension before sleeping were independently associated with difficulty initiating sleep in patients with heart failure [
      • Amisaki R.
      • Kato M.
      • Fujiyama M.
      • Matsuda E.
      • Hattori Y.
      • Hirai M.
      • et al.
      Difficulty initiating sleep in patients with heart failure: impact of left atrial pressure.
      ]. Several concerns have been raised.

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